Endocrine Abstracts

Background: Glucocorticoid (GC) therapy is standard of care of management of Duchenne Muscular Dystrophy (DMD) but its use is associated with a range of side-effects. Weight gain leading to significant obesity is common in GC-treated boys.Aim(s): To evaluate changes in growth parameters: height-SDS, weight-SDS, body mass index (BMI)-SDS following initiation of GC in DMD.Methods: Between 2013-2019, 26 boys with DMD were commenced on...

Background: Glucocorticoid (GC) therapy is the standard management for Duchenne Muscular Dystrophy (DMD), but its use is associated with significant side effects, including weight gain. Limited research exists on the impact of GC initiation on body composition in DMD, particularly regarding the timing of fat mass increase.Objective: This study aimed to assess changes in growth parameters, namely height-SDS, weight-SDS, b...